Job Description 100+ novel therapeutic protein candidates are evaluated per year regarding their immunogenicity potential by the NBC-MI Immunogenicity group.
You will work in a collaborative team that is applying a multitude of different technologies such as MAPPs (MHC associated peptide proteomics), human in vitro DC & T cell assays, serological ADA profiling, human in vitro B cell expansion assays and in silico methodologies.
In this position, you will have the opportunity to generate high impact data on a highly visible project and work together in a diverse team of immunogenicity experts.
Your responsibilities: Your responsibilities include, but are not limited to:
• Design/execute experiments and identify next steps based on analysis of own data and data from other lab contributors. Independently modify existing lab techniques and implement techniques new to the lab • Communicate results and conclusions to project meetings. Provide input to internal / external publications including writing relevant sections • Collaborate across project team labs to design and implement new assays and techniques.. Suggest/build new network connections within existing project teams. • Routinely train members of lab and broader project team in familiar techniques • Take over organizational responsibility (such as equipment power user, lab safety rep) • Accountable for increasingly complex experiments; key contributor to the success of drug discovery, technology, and/or early development projects. Brings ideas from a concept or question to a decision in experimental design, based on previous observations • Design and perform cell-based assays and/or ELISA assays for immunogenicity potential assessment under minimal supervision. Compile and analyze data under minimal supervision
Minimum requirementsWhat you’ll bring to the role: • Successfully completed BSc or MS degree in Biology / Biotechnology and Biochemistry or related field • At least 2 years of experience in industrial or academic setting in immunology • Fluent English, German language proficiency of advantage • Strong hands-on experience in ELISA • Experience in FLISA assays,Biacore and Flow Cytometry of advantage • Ability to analyze and interpret scientific information critically and objectively • Strong inter-personal skills ensuring close collaboration with team members
Start date: October 1st 2020 Duration: 1 year
Why consider Novartis? 750 million. That’s how many lives our products touch. And while we’re proud of that, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?
We believe the answers are found when curious, courageous and collaborative people like you are empowered to ask new questions, make bolder decisions and take smarter risks.
We are Novartis. Join us and help reimagine medicine.
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