PhD Position in Neuroscience Discovery (2.5 years) in Basel

Who We Are:

At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity, and on seeing each other’s differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing – and is seeking people who have the same goals for themselves.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

The Position:

The candidate will join the Neuroscience Discovery Department at Roche headquarters, located in Basel, Switzerland. They will interact closely with the team of research associates and scientists working to investigate blood-brain-barrier (BBB) biology in neurological diseases by investigating receptor-mediated transport across the BBB.

The successful candidate will focus on investigating the relationship between barriers of the central nervous system (CNS) and the dynamics of CNS pathologies in both in-vivo and in-vitro models.

You will:

• Design and conduct experiments to investigate compound efficacy across the BBB
• Present work internally and at international conferences
• Publish work in peer-reviewed journals          
• Apply analytical judgment in interpreting experimental data
• Ability to work effectively and independently according to time-lines
• Excellent organizational skills, personal initiative and detail oriented
• Good communication and presentation skills, fluent in English

Who You Are:

You’re someone who wants to influence your own development. You’re looking for a company where you have the opportunity to pursue your interests across functions and geographies, and where a job title is not considered the final definition of who you are, but the starting point.
For this position you bring the following qualifications:

• Master’s degree in Neuroscience
• Additional background in biochemistry and cell biology
• Experience in applied biomedical research in neuroinflammatory diseases
• At least 2 years hands-on experience with in-vivo models of neurological diseases
• Proven ability in brain stereotactic surgery, administration techniques and tissue collection
• Experience with mammalian cell culture, isolating cells and establishing cultures
• Experience with in-vivo viral-based screening
• Knowledgeable of state-of-the-art imaging techniques, specifically both in Bioluminescence Imaging and in vitro confocal microscopy
• Experience with phenotypic characterization of mouse and human immune cells
• Experienced in GraphPad Prism, FIJI (ImageJ), AxioVision and Zen, Case Viewer and Adobe Applications
• Swiss LTK1 Certification - in order to legally work with animal models in Switzerland
• Preferably at least 1 year working in a pharmaceutical environment

For questions please call the Recruiting Team Switzerland +41 61 682 25 50

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