The Particles@Barriers group seeks to acquire a mechanistic understanding on the interaction of particulate materials with biological barriers. In particular, we are interested in the correlation of physicochemical particle properties with barrier translocation and biological effects in order to support the safe design of particles and the development of novel particle-based therapeutic concepts.
In this project, funded by the Swiss National Science Foundation, you will explore indirect embryo-fetal risks of industrially and medically relevant nanomaterials at the placental barrier using advanced human in vitro andex vivo placenta models (placental explant cultures from early and late pregnancy and perfusion of term placentas). A particular focus will be on the potential interference of nanomaterials with inflammatory, vascular and endocrine signaling form the placental tissue. The project is carried out under the supervision of Dr. T. Bürki and is in collaboration with the Cantonal Hospital of St. Gallen (KSSG) and the University of Geneva.
You will have the opportunity to work in a very interdisciplinary, dynamic environment at the forefront of the field.
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We offer a challenging position at a materials research institution with outstanding infrastructure and an interdisciplinary surrounding. You can expect significant support and guidance from established scientists during the whole of your project. The work will be carried out at Empa St. Gallen. The position is available upon agreement.
25-03-2024
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