Student Internship - automated analysis of rodent models for neurodevelopmental disorders in Basel

At Roche, we believe it's urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are brave in both decision and action, we believe that good business means a better world.

The in-vivo group within the Neurosymptomatic domains and neurodevelopmental disorders sections of the Neuroscience department consists of four laboratory heads and eight technicians. The group is responsible for providing the full range of expertise and technologies to profile molecules in preclinical models of brain disorders, throughout the course of the drug discovery process.

We are looking for a Master’s student who will characterise rodent models for neurodevelopmental disease (NDD) through home cage monitoring (HCM). The more naturalistic setting of HCM enables longitudinal measurement, improving the signal to noise ratio compared to typical behavioural testing that is short in duration and prone to disturbance. HCM is important in the search of more predictive preclinical models of human disease. There is the opportunity to write a Master thesis while staying with us.

Your main responsibility will be:

• learning to use an automated home cage system to characterise (genetic) rodent models of neurodevelopmental disorders such as autism & schizophrenia
• adapting and writing computer operated protocols
• scoring mouse & rat behaviour to correlate manual to automated observations
• design and execute experiments to assess behaviour longitudinallyhandling mice & rats and injecting compounds
• analyse data with dedicated commercial software as well as customised analysis tools

Who You Are

You’re someone who wants to influence your own development. You are looking for a company where you receive a chance to pursue your interests across functions and geographies. Working in a multi-cultural environment motivates you. As fast learner you actively drive the quality of the requirements.

You are currently enrolled in your last or penultimate year of a Master program. You are studying in the field of Biology, Neuropsychology, or Bioinformatics with a keen interest in behavioural processes and data processing.

Moreover you are/have:

• Willingness and interest to work with laboratory animals
• License to work with laboratory animals
• An independent attitude with an eye for (technical) detail and troubleshooting
• Eager to handle and analyse large data sets, knowledge in data processing
• An excellent command of the English language
• A team player attitude

Information about application documents and start date:

The preferred start date of this internship is as soon as possible. Along with your CV, please include a cover letter outlining how your interests and experience align with this job posting, career plans, and expectations for this internship. Please note that the cover letter is mandatory. Please also indicate your preferred starting date and internship’s duration.

Due to regulations non-EU/EFTA citizens must provide a certificate from the university stating that an internship is mandatory as part of the application documents.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

If you still have questions then please check our FAQs and videos oncareers.roche.ch/faq.

Tags: ROiBY, ROiBI