Job Description 1 in 10 adults in Europe suffer from autoimmune or inflammatory diseases. The Department of Autoimmunity, Transplantation and Inflammation adresses this steadily growing burden on public Health with Research in the fields of rheumatology, dermatology and beyond.
We are looking for a postdoctoral fellow to investigate the biology and downstream signaling of AD-associated cytokines including IL-17C on relevant skin target cells, in human ex vivo skin biopsies and in cytokine reporter/conditional knock-out mice. We provide state-of-the-art flow cytometry, proteomics and transcriptomics as well as biochemical and molecular technologies. In-house expertise in CRISPR, immunology and translational research as well as a variety of tools to interrogate cytokine expression, and pathway activation are available. The successful candidate should have experience in use of genetically modified mice and working with primary human skin and tissues to analyze cellular and biochemical regulation of cytokine signaling and should have knowledge of immunology. Knowledge in use of CRISPR and generation and evaluation of reporter and conditional knockout mice is highly desirable.
#PhD
Minimum requirementsWhat you'll bring to the role: • PhD in molecular and cell biology and/or immunology (PhD students in the last year of their thesis work, are eligible to apply) Fluency in English, Knowledge of the German language will be advantageous • Knowledge of skin immunology, translational research and/or IL-17-receptor biology are a plus • Expertise in CRISPR and transgenic mouse research are highly regarded • Expertise in bioinformatics to interrogate complex datasets would be desirable • Strong publication record • Excellent analytical, communication and organizational skills
Why consider Novartis? 750 million. That’s how many lives our products touch. And while we’re proud of that, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives? We believe the answers are found when curious, courageous and collaborative people like you are empowered to ask new questions, make bolder decisions and take smarter risks.
We are Novartis. Join us and help reimagine medicine.
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